Changes in myocardial and vascular receptors in heart failure.

  • Mila Bristow
  • Published 1993 in Journal of the American College of Cardiology


Heart failure results in dramatic changes in certain neurotransmitter and hormone receptors. The majority of the changes occur in the heart and generally can be classified as regulatory phenomena that withdraw the failing heart from adrenergic stimulation. Of these, the most prominent is beta 1-receptor downregulation. Changes in vascular receptors are much… (More)