Changes in mechanical, chemical, and thermal sensitivity of the cornea after topical application of nonsteroidal anti-inflammatory drugs.

@article{Acosta2005ChangesIM,
  title={Changes in mechanical, chemical, and thermal sensitivity of the cornea after topical application of nonsteroidal anti-inflammatory drugs.},
  author={M. C. Acosta and L. Berenguer-Ruiz and A. Garc{\'i}a-G{\'a}lvez and D. Perea-Tortosa and J. Gallar and C. Belmonte},
  journal={Investigative ophthalmology \& visual science},
  year={2005},
  volume={46 1},
  pages={
          282-6
        }
}
PURPOSE In addition to their well-known anti-inflammatory actions, some of the nonsteroidal anti-inflammatory drugs (NSAIDs) appear to have an analgesic effect. In human subjects, the changes in threshold and intensity of sensations evoked by mechanical, chemical, and thermal stimulation of the cornea induced by topical administration of two commercial NSAIDs, diclofenac sodium (Voltaren; Novartis, Basel, Switzerland) and flurbiprofen (Ocuflur; Allergan, Irvine, CA), were studied. METHODS… Expand
Comparative effects of the nonsteroidal anti-inflammatory drug nepafenac on corneal sensory nerve fibers responding to chemical irritation.
Corneal nerves in health and disease.
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