Changes in matrix protein biochemistry and the expression of mRNA encoding matrix proteins and metalloproteinases in posterior tibialis tendinopathy

@inproceedings{Corps2012ChangesIM,
  title={Changes in matrix protein biochemistry and the expression of mRNA encoding matrix proteins and metalloproteinases in posterior tibialis tendinopathy},
  author={Anthony N. Corps and Andrew H N Robinson and Rebecca L. Harrall and Nicholas C. Avery and Valerie A. Curry and Brian L. Hazleman and Graham J. P. Riley},
  booktitle={Annals of the rheumatic diseases},
  year={2012}
}
OBJECTIVES Adult-acquired flat foot secondary to a dysfunctional posterior tibialis tendon (PTT) is often treated by surgical transfer of the flexor digitorum longus tendon (FDLT). In this study, the authors compared normal PTT, stage II dysfunctional PTT and replacement FDLT, aiming to define changes in collagen modification, glycosaminoglycan (GAG) and the expression of matrix and metalloproteinase mRNA. METHODS Normal PTTs were obtained from patients with no history of tendon problems… CONTINUE READING
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