Changes in lung eicosanoid content during normal and abnormal transition in perinatal lambs.


To study the potential contribution of eicosanoids in maintaining high vascular tone in utero or in modulating resistance during the normal or abnormal transition of the pulmonary circulation, we performed serial measurements of hemodynamic parameters and lung eicosanoid content in perinatal sheep with and without pulmonary hypertension. Prostacyclin (6… (More)


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