Changes in lipid phase behaviour in human myelin during maturation and aging. Involvement of lipid peroxidation.

Abstract

The biophysical properties of human myelin isolated from white matter of patients aged two months to 74 years were investigated using wide-angle X-ray diffraction. The myelin transition temperature increased from 13 degrees C to 65 degrees C as age increased from two months to 17 years, demonstrating an increase in the myelin lipid stability. Following this… (More)

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@article{Chia1983ChangesIL, title={Changes in lipid phase behaviour in human myelin during maturation and aging. Involvement of lipid peroxidation.}, author={Liang-Tien Chia and J. E. Thompson and Mario A. Moscarello}, journal={FEBS letters}, year={1983}, volume={157 1}, pages={155-8} }