Changes in left ventricular diastolic function 6 months after nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy.

@article{Nagueh1999ChangesIL,
  title={Changes in left ventricular diastolic function 6 months after nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy.},
  author={Sherif F. Nagueh and Nasser M. Lakkis and Katherine Middleton and Donna M. Killip and William A. Zoghbi and Miguel Angel Qui{\~n}ones and William H. Spencer},
  journal={Circulation},
  year={1999},
  volume={99 3},
  pages={344-7}
}
BACKGROUND Nonsurgical septal reduction therapy (NSRT) decreases left ventricular outflow tract (LVOT) gradient and improves symptoms in patients with hypertrophic obstructive cardiomyopathy (HOCM). NSRT effects on LV/left ventricular diastolic function are currently unknown. METHODS AND RESULTS HOCM patients (n=29) had Doppler echocardiography at baseline and 6 months after NSRT to evaluate changes in LV volume, pre-A-wave pressure, early diastolic mitral annulus velocity (Ea) by tissue… CONTINUE READING