Changes in keratin expression during metastatic progression of breast cancer: impact on the detection of circulating tumor cells.

@article{Joosse2012ChangesIK,
  title={Changes in keratin expression during metastatic progression of breast cancer: impact on the detection of circulating tumor cells.},
  author={Simon A Joosse and Juliane Hannemann and Julia Sp{\"o}tter and Andreas Bauche and Antje Andreas and Volkmar Mueller and Klaus Pantel},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2012},
  volume={18 4},
  pages={
          993-1003
        }
}
PURPOSE Circulating tumor cells (CTC) might function as early markers for breast cancer metastasis or monitoring therapy efficacy. Enrichment and identification of CTCs are based on epithelial markers that might be modulated during epithelial-mesenchymal transition. Little is known about the expression of keratins in CTCs and whether all CTCs can be detected with antibodies directed against a limited panel of keratins. EXPERIMENTAL DESIGN Protein expression of keratin 2, 4-10, 13-16, 18, and… CONTINUE READING

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Recent advances in metastasis research

T Molloy, LJ van'tVeer
  • Curr Opin Genet Dev
  • 2008
VIEW 3 EXCERPTS
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