Changes in jejunal mucosa after long-term feeding of germfree rats with gluten.

Abstract

BACKGROUND Coeliac disease (CD) or gluten-sensitive enteropathy is a chronic gastrointestinal disease of children and adults. An experimental model using inbred germfree rats has been developed to study the effects of intragastric gliadin application on intestinal mucosa. METHODS AVN strain Wistar rats (inbred F 87)-germfree were used. Gliadin was applied… (More)

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