Changes in isoprenaline-induced endothelium-dependent and -independent relaxations of aorta in long-term STZ-diabetic rats: reversal effect of dietary vitamin E.


1. The present study concerns in vitro isoprenaline (ISO)-induced relaxation of aortic rings of long-term streptozotocin (STZ)-diabetic and nondiabetic rats, both with and without dietary vitamin E supplementation. 2. Incubation with propranolol, NG-nitro-L-arginine methyl ester and methylene blue, as well as absence of endothelium, all negatively affect… (More)


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