Changes in inflammatory cytokines are related to impaired glucose tolerance in offspring of type 2 diabetic subjects.

@article{Ruotsalainen2006ChangesII,
  title={Changes in inflammatory cytokines are related to impaired glucose tolerance in offspring of type 2 diabetic subjects.},
  author={Eija Ruotsalainen and Urpu Salmenniemi and Ilkka Vauhkonen and Jussi Pihlajam{\"a}ki and Kari Punnonen and Sakari Kainulainen and Markku Laakso},
  journal={Diabetes care},
  year={2006},
  volume={29 12},
  pages={2714-20}
}
OBJECTIVE We sought to determine whether levels of inflammatory markers and different cytokines are abnormal in nondiabetic offspring of type 2 diabetic subjects. RESEARCH DESIGN AND METHODS Cytokine levels were measured in 19 healthy control subjects and 129 offspring of patients with type 2 diabetes (109 with normal glucose tolerance [NGT] and 20 with impaired glucose tolerance [IGT]). Insulin sensitivity was determined with the hyperinsulinemic-euglycemic clamp, insulin secretion with the… CONTINUE READING
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