Changes in hyaluronan production and metabolism following ischaemic stroke in man.

@article{AlQteishat2006ChangesIH,
  title={Changes in hyaluronan production and metabolism following ischaemic stroke in man.},
  author={Ahmed Al'Qteishat and John Gaffney and Jerzy Krupinski and Francisco Rubio and David West and Shant Kumar and Patricia Kumar and Nicholas Mitsios and Mark Slevin},
  journal={Brain : a journal of neurology},
  year={2006},
  volume={129 Pt 8},
  pages={2158-76}
}
The extent of recovery from stroke is dependent on the survival of neurons, particularly in peri-infarcted regions. Angiogenesis is critical for the development of new microvessels and leads to re-formation of collateral circulation, reperfusion and better recovery. Hyaluronan (HA) is an important component of the brain extracellular matrix and a regulator of cellular differentiation, migration, proliferation and angiogenesis. We have found that the production of total HA and low molecular mass… CONTINUE READING

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