Changes in hippocampal adenosine efflux, ATP levels, and synaptic transmission induced by increased temperature.

@article{Masino2001ChangesIH,
  title={Changes in hippocampal adenosine efflux, ATP levels, and synaptic transmission induced by increased temperature.},
  author={Susan A. Masino and Serena Latini and Francesca Bordoni and Felicita Pedata and Thomas V. Dunwiddie},
  journal={Synapse},
  year={2001},
  volume={41 1},
  pages={58-64}
}
Previous studies have demonstrated that when the temperature of hippocampal brain slices is increased, there is a corresponding depression of synaptic potentials mediated by an increased activation of presynaptic adenosine A(1) receptors. The present experiments demonstrate that when the temperature of hippocampal slices is raised from 32.5 degrees C to either 38.5 degrees C or 40.0 degrees C there is a marked, temperature-dependent increase in the efflux of endogenous adenosine and a… CONTINUE READING