Changes in gingival crevicular fluid interleukin-4 and interferon-gamma in patients with chronic periodontitis before and after periodontal initial therapy.

@article{Tsai2007ChangesIG,
  title={Changes in gingival crevicular fluid interleukin-4 and interferon-gamma in patients with chronic periodontitis before and after periodontal initial therapy.},
  author={C C Tsai and Chia-Hsin Ku and Ya-Ping Ho and K Ho and Y Wu and Chun-Cheng Hung},
  journal={The Kaohsiung journal of medical sciences},
  year={2007},
  volume={23 1},
  pages={1-7}
}
Cytokines are pivotal to the immune response of chronic periodontitis. The present study investigated the changes of gingival crevicular fluid (GCF) interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) in patients with chronic periodontitis before and after initial nonsurgical periodontal therapy (NSPT). GCF was collected from 17 patients by means of Periopaper at baseline and 1 month after NSPT. IL-4 and IFN-gamma were measured by enzyme-linked immunoabsorbent assay. NSPT resulted in… CONTINUE READING