Changes in gene expression of ARPE-19 cells in response to vitreous treatment.

@article{Fan2002ChangesIG,
  title={Changes in gene expression of ARPE-19 cells in response to vitreous treatment.},
  author={Wei Fan and Jing Juan Zheng and Stephen C. Peiper and Barbara J. Mclaughlin},
  journal={Ophthalmic research},
  year={2002},
  volume={34 6},
  pages={357-65}
}
PURPOSES The purpose of this study is to determine the changes in gene expression by a human retinal pigment epithelium (RPE) cell line (ARPE-19) in response to vitreous treatment, which induces RPE proliferation and phenotypic changes in vitro that mimic the repair response observed in vivo during proliferative vitreoretinopathy. METHODS ARPE-19 cells were grown for more than 4 weeks and their gene expression studied in: (1) subconfluent cultures treated with 50% human vitreous for 72 h; (2… CONTINUE READING