Changes in gene expression caused by insect venom immunotherapy responsible for the long-term protection of insect venom-allergic patients.

@article{Niedoszytko2011ChangesIG,
  title={Changes in gene expression caused by insect venom immunotherapy responsible for the long-term protection of insect venom-allergic patients.},
  author={Marek Niedoszytko and Marcel Bruinenberg and Jan G R de Monchy and Rinse K. Weersma and Cisca Wijmenga and Ewa Jassem and Joanne NG Oude Elberink},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  year={2011},
  volume={106 6},
  pages={
          502-10
        }
}
BACKGROUND Insect venom immunotherapy (VIT) is the only causative treatment of insect venom allergy (IVA). The immunological mechanism(s) responsible for long-term protection achieved by VIT are largely unknown. A better understanding is relevant for improving the diagnosis, prediction of anaphylaxis, and monitoring and simplifying treatment of IVA. OBJECTIVE To find genes that are differentially expressed during the maintenance phase of VIT and after stopping, to get clues about the pathways… CONTINUE READING
BETA

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