Changes in gene expression associated with developmental arrest and longevity in Caenorhabditis elegans.

@article{Jones2001ChangesIG,
  title={Changes in gene expression associated with developmental arrest and longevity in Caenorhabditis elegans.},
  author={S J Jones and Donald L. Riddle and Anatoli Pouzyrev and Victor E. Velculescu and L G Hillier and Sean R. Eddy and Shawn L. Stricklin and D. L. Baillie and Robert H. Waterston and Marco A. Marra},
  journal={Genome research},
  year={2001},
  volume={11 8},
  pages={1346-52}
}
Gene expression in a developmentally arrested, long-lived dauer population of Caenorhabditis elegans was compared with a nondauer (mixed-stage) population by using serial analysis of gene expression (SAGE). Dauer (152,314) and nondauer (148,324) SAGE tags identified 11,130 of the predicted 19,100 C. elegans genes. Genes implicated previously in longevity were expressed abundantly in the dauer library, and new genes potentially important in dauer biology were discovered. Two thousand six hundred… CONTINUE READING
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