Changes in expression of differentiation markers between normal ovarian cells and derived tumors.

@article{Niekerk1993ChangesIE,
  title={Changes in expression of differentiation markers between normal ovarian cells and derived tumors.},
  author={C C van Niekerk and Frans Charles Servatius Ramaekers and Antonius G. J. M. Hanselaar and J. Aldeweireldt and Lambert G. Poels},
  journal={The American journal of pathology},
  year={1993},
  volume={142 1},
  pages={157-77}
}
The marker profile of 18 samples of normal human ovarian tissues and 138 samples of their derived tumors was established using 51 monoclonal antibodies directed against intermediate filaments, ovarian carcinoma-specific antigens, general tumor-associated antigens and MHC-I/II antigens. Our data show that vimentin and keratins 7, 8, 18, and 19 were found in both epithelial and some nonepithelial ovarian tumors. Several tumor samples contained additional keratins 4, 10, 13, and 14, as well as… CONTINUE READING

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