Changes in expression and localization of X-linked inhibitor of apoptosis protein (XIAP) in follicular granulosa cells during atresia in porcine ovaries.

@article{Cheng2008ChangesIE,
  title={Changes in expression and localization of X-linked inhibitor of apoptosis protein (XIAP) in follicular granulosa cells during atresia in porcine ovaries.},
  author={Yuan Guo Cheng and Akihisa Maeda and Yasufumi Goto and Fuko Matsuda and Takashi Miyano and Naoko Inoue and Kazuhiro Sakamaki and Noboru Manabe},
  journal={The Journal of reproduction and development},
  year={2008},
  volume={54 6},
  pages={454-9}
}
Follicular selection predominantly depends on granulosa cell apoptosis in porcine ovaries, but the molecular mechanisms regulating the induction of apoptosis in granulosa cells during follicular selection remain incompletely understood. To determine the role of X-linked inhibitor of apoptosis protein (XIAP), which suppresses caspase-3, -7 and -9 activities and acts as an endogenous inhibitor of apoptotic cell death, in the regulation of granulosa cell apoptosis during follicular atresia, we… CONTINUE READING

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