Changes in enteric neurone phenotype and intestinal functions in a transgenic mouse model of enteric glia disruption.

@article{Aub2006ChangesIE,
  title={Changes in enteric neurone phenotype and intestinal functions in a transgenic mouse model of enteric glia disruption.},
  author={A C Aub{\'e} and Julie Cabarrocas and Jan Niklas Bauer and David Philippe and P Aubert and F Doulay and Roland S Liblau and Jean Paul Galmiche and Michel Neunlist},
  journal={Gut},
  year={2006},
  volume={55 5},
  pages={630-7}
}
AIMS The influence of enteric glia on the regulation of intestinal functions is unknown. Our aim was to determine the phenotype of enteric neurones in a model of glia alterations and the putative changes in intestinal motility and permeability. METHODS Transgenic mice expressing haemagglutinin (HA) in glia were used. Glia disruption was induced by injection of activated HA specific CD8+ T cells. Control mice consisted of non-transgenic littermates injected with activated HA specific CD8+ T… CONTINUE READING

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