Changes in energy metabolites, cGMP and intracellular pH during cortical spreading depression.

@article{Gault1994ChangesIE,
  title={Changes in energy metabolites, cGMP and intracellular pH during cortical spreading depression.},
  author={L M Gault and C. W. Lin and Joseph C. LaManna and W. David Lust},
  journal={Brain research},
  year={1994},
  volume={641 1},
  pages={176-80}
}
The spatial and temporal distribution of cerebral metabolites and pHi were examined in the cortex during spreading depression. Acidification and marked depression in the energy status of the tissue was evident at the wavefront of spreading depression. In its aftermath, the residual activation of glycolysis and accumulation of cGMP persisted for minutes… CONTINUE READING