Changes in contraction-induced phosphorylation of AMP-activated protein kinase and mitogen-activated protein kinases in skeletal muscle after ovariectomy.

@article{Wohlers2009ChangesIC,
  title={Changes in contraction-induced phosphorylation of AMP-activated protein kinase and mitogen-activated protein kinases in skeletal muscle after ovariectomy.},
  author={Lindsay Michelle Wohlers and Sean Mc Sweeney and Christopher W Ward and Richard M Lovering and Espen E. Spangenburg},
  journal={Journal of cellular biochemistry},
  year={2009},
  volume={107 1},
  pages={171-8}
}
Recent evidence suggests that ovarian hormones contribute to altered function of skeletal muscle, however the signaling processes thought to regulate muscle function remain undefined in females. Thus, the purpose of this investigation is to determine if ovarian hormone status is critical for contraction-induced activation of AMPK or MAPK in skeletal muscle. Female mice were divided into two groups, ovariectomy (OVX) and SHAM, which were then subjected to in situ isometric contractile protocols… CONTINUE READING