Changes in contractile properties with selective digestion of connectin (titin) in skinned fibers of frog skeletal muscle.

@article{Higuchi1992ChangesIC,
  title={Changes in contractile properties with selective digestion of connectin (titin) in skinned fibers of frog skeletal muscle.},
  author={Hirokazu Higuchi},
  journal={Journal of biochemistry},
  year={1992},
  volume={111 3},
  pages={291-5}
}
Changes in contractile properties of mechanically skinned fibers were examined when connectin in the fibers was selectively digested by a low concentration (0.25 microgram/ml) of trypsin. Resting tension and isometric active tension were reduced as the digestion of the connectin progressed; the rate of reduction of active tension was larger than that of resting tension. Maximum shortening speed and calcium ion sensitivity of active tension were not changed by the digestion. Electron micrographs… CONTINUE READING

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