Changes in cognition and behaviour in amyotrophic lateral sclerosis: nature of impairment and implications for assessment.

@article{Goldstein2013ChangesIC,
  title={Changes in cognition and behaviour in amyotrophic lateral sclerosis: nature of impairment and implications for assessment.},
  author={Laura H Goldstein and Sharon Abrahams},
  journal={The Lancet. Neurology},
  year={2013},
  volume={12 4},
  pages={368-80}
}
Increased awareness of cognitive and behavioural change in amyotrophic lateral sclerosis has been driven by various clinic-based and population-based studies. A frontotemporal syndrome occurs in a substantial proportion of patients, a subgroup of whom present with frontotemporal dementia. Deficits are characterised by executive and working-memory impairments, extending to changes in language and social cognition. Behaviour and social cognition abnormalities are closely similar to those reported… CONTINUE READING