Changes in circulating postprandial proinflammatory cytokine concentrations in diet-controlled type 2 diabetes and the effect of ingested fat.

@article{Manning2004ChangesIC,
  title={Changes in circulating postprandial proinflammatory cytokine concentrations in diet-controlled type 2 diabetes and the effect of ingested fat.},
  author={Patrick J. Manning and Wayne H. F. Sutherland and Gavin P. Hendry and Sylvia A. de Jong and Michelle M McGrath and Sheila M. Williams},
  journal={Diabetes care},
  year={2004},
  volume={27 10},
  pages={2509-11}
}
The proinflammatory cytokines interleukin (IL)-6 and tumor necrosis factor (TNF)are thought to impair insulin signaling (1,2), and abnormally high levels of them are associated with insulin resistance (3,4) and type 2 diabetes (3,5). In patients with type 2 diabetes, a meal rich in fat, mainly in the form of sausages and butter, increases postprandial plasma concentrations of IL-6 and TNF, whereas a meal rich in carbohydrates has less effect (5). Current dietary recommendations for diabetic… CONTINUE READING
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