Changes in circulating biomarkers of muscle atrophy, inflammation, and cartilage turnover in patients undergoing anterior cruciate ligament reconstruction and rehabilitation.

@article{Mendias2013ChangesIC,
  title={Changes in circulating biomarkers of muscle atrophy, inflammation, and cartilage turnover in patients undergoing anterior cruciate ligament reconstruction and rehabilitation.},
  author={Christopher L Mendias and Evan B. Lynch and Max E. Davis and Elizabeth R Sibilsky Enselman and Julie A. Harning and Paul D Dewolf and Tarek A Makki and Asheesh Bedi},
  journal={The American journal of sports medicine},
  year={2013},
  volume={41 8},
  pages={1819-26}
}
BACKGROUND After anterior cruciate ligament (ACL) reconstruction, there is significant atrophy of the quadriceps muscles that can limit full recovery and place athletes at risk for recurrent injuries with return to play. The cause of this muscle atrophy is not fully understood. HYPOTHESIS Circulating levels of proatrophy, proinflammatory, and cartilage turnover cytokines and biomarkers would increase after ACL reconstruction. STUDY DESIGN Descriptive laboratory study. METHODS Patients (N… CONTINUE READING
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