Changes in cerebral blood flow, cerebral metabolites, and breathing movements in the sheep fetus following asphyxia produced by occlusion of the umbilical cord.

@article{Yan2009ChangesIC,
  title={Changes in cerebral blood flow, cerebral metabolites, and breathing movements in the sheep fetus following asphyxia produced by occlusion of the umbilical cord.},
  author={Edwin Bingbing Yan and Ana A. Baburamani and Adrian Mark Walker and David W Walker},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2009},
  volume={297 1},
  pages={R60-9}
}
Severe global fetal asphyxia, if caused by a brief occlusion of the umbilical cord, results in prolonged cerebral hypoperfusion in fetal sheep. In this study, we sought evidence to support the hypothesis that cerebral hypoperfusion is a consequence of suppressed cerebral metabolism. In the 24 h following complete occlusion of the umbilical cord for 10 min, sagittal sinus blood flow velocity was significantly decreased for up to 12 h. Capillary blood flow, measured using microspheres, decreased… CONTINUE READING

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