Changes in central dopaminergic systems with the expression of Shh or GDNF in mice perinatally exposed to bisphenol-A.

@article{Miyagawa2007ChangesIC,
  title={Changes in central dopaminergic systems with the expression of Shh or GDNF in mice perinatally exposed to bisphenol-A.},
  author={Kazuya Miyagawa and Minoru Narita and Michiko Narita and Keiichi Niikura and Hisahiko Akama and Yuri Tsurukawa and Tsutomu Suzuki},
  journal={Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology},
  year={2007},
  volume={27 2},
  pages={69-75}
}
In the previous study, we reported that exposure to bisphenol-A induced the potentiation of dopamine receptor functions in the mouse limbic area, resulting in supersensitivity to methamphetamine-induced pharmacological actions. The present study was undertaken to investigate whether prenatal exposure to bisphenol-A could produce morphological change in dopaminergic neuron and the pattern of expression of genes regulating the dopaminergic neuron development. Here we found that prenatal and… CONTINUE READING