Changes in cell spreading and cytoskeletal organization are induced by adhesion to a fibronectin-fibrin matrix.

@article{Corbett1996ChangesIC,
  title={Changes in cell spreading and cytoskeletal organization are induced by adhesion to a fibronectin-fibrin matrix.},
  author={Siobhan A. Corbett and Claire L Wilson and Jean E. Schwarzbauer},
  journal={Blood},
  year={1996},
  volume={88 1},
  pages={158-66}
}
Plasma fibronectin (pFN) cross-linked to fibrin during the injury response provides a provisional matrix required for cells to begin tissue repair. Using a synthetic matrix of pFN and fibrin as a substrate for cell adhesion and spreading, we have determined that pFN covalently cross-linked to fibrin into a complex multimer is functionally distinct from pFN immobilized onto a plastic surface. NIH-3T3 cells on a FN-fibrin matrix reach 50% of the maximal cell area of cells spread on FN-coated… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Role of fibronectin in normal wound healing.

International wound journal • 2015
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Similar Papers

Loading similar papers…