Changes in catalase, glutathione peroxidase and glutathione-S-transferase activities in the liver of newts exposed to 2-methyl-4-chlorophenoxyacetic acid (MCPA).

@article{Santagostino1989ChangesIC,
  title={Changes in catalase, glutathione peroxidase and glutathione-S-transferase activities in the liver of newts exposed to 2-methyl-4-chlorophenoxyacetic acid (MCPA).},
  author={A. Santagostino and M. Colleoni and E. Arias and N. Pacces Zaffaroni and T. Zavanella},
  journal={Pharmacology & toxicology},
  year={1989},
  volume={65 2},
  pages={
          136-9
        }
}
  • A. Santagostino, M. Colleoni, +2 authors T. Zavanella
  • Published 1989
  • Biology, Medicine
  • Pharmacology & toxicology
  • Activities of catalase, glutathione peroxidase (GSH-Px) and glutathione-S-transferase (GST) were measured in livers of the crested newt (Urodele Amphibian) after 16 days of percutaneous exposure to the herbicide Agroxone 3, a commercial formulation of 2-methyl-4-chlorophenoxyacetic acid (MCPA) containing 25% MCPA as sodium salt and 75% wetting and dispersing ingredients. Animals of both sexes were exposed to 800 p.p.m. of the active ingredient. There was a three-fold increase in catalase and a… CONTINUE READING
    8 Citations
    Effect of the herbicide 4-CPA on human erythrocyte antioxidant enzymes in vitro
    • 7
    Chronic cannabinoid, CP-55,940, administration alters biotransformation in the rat.
    • 34
    Isolated hepatocytes of rainbow trout (Oncorhynchus mykiss) as a tool to discriminate between differently contaminated small river systems.
    • M. Strmac, T. Braunbeck
    • Biology, Medicine
    • Toxicology in vitro : an international journal published in association with BIBRA
    • 2000
    • 45
    Sister chromatid exchanges in chick embryos after treatment with the phenoxy herbicide mcpa
    • E. Arias
    • Biology, Medicine
    • Environmental and molecular mutagenesis
    • 1992
    • 2

    References

    SHOWING 1-10 OF 20 REFERENCES
    Interaction of chlorophenoxyalkyl acid herbicides with rat-liver glutathione S-transferases.
    • P. Dierickx
    • Chemistry, Medicine
    • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
    • 1983
    • 18
    A sex difference in hepatic glutathione S-transferase B and the effect of hypophysectomy.
    • 42
    Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.
    • 14,426
    • PDF
    Peroxisomes in the liver of frog, Bombina orientalis.
    • 9
    Hypolipidemia and peroxisome proliferation induced by phenoxyacetic acid herbicides in rats.
    • 80