Changes in cardiovascular responsiveness and cardiotoxicity elicited during binge administration of Ecstasy.

@article{Badon2002ChangesIC,
  title={Changes in cardiovascular responsiveness and cardiotoxicity elicited during binge administration of Ecstasy.},
  author={Lisa A Badon and Alissa Hicks and Kevin C. Lord and Brian A Ogden and Suzanne Meleg-Smith and Kurt J Varner},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2002},
  volume={302 3},
  pages={898-907}
}
The recreational use of 3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) is often characterized by a repeated pattern of frequent drug administrations (binge) followed by a period of abstinence. Radiotelemetry was used to characterize the cardiovascular responses elicited during three MDMA binges (3 or 9 mg/kg b.i.d. for 4 days), each of which was… CONTINUE READING