Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation

@inproceedings{Testa2016ChangesIB,
  title={Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation},
  author={Gabriella Testa and Erica Staurenghi and Chiara Zerbinati and Simona Gargiulo and Luigi Iuliano and Giorgio Giaccone and Fausto Fant{\'o} and Giuseppe Poli and Gabriella Leonarduzzi and Paola Gamba},
  booktitle={Redox biology},
  year={2016}
}
Alzheimer's disease (AD) is a gradually debilitating disease that leads to dementia. The molecular mechanisms underlying AD are still not clear, and at present no reliable biomarkers are available for the early diagnosis. In the last several years, together with oxidative stress and neuroinflammation, altered cholesterol metabolism in the brain has become increasingly implicated in AD progression. A significant body of evidence indicates that oxidized cholesterol, in the form of oxysterols, is… CONTINUE READING

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