Changes in brain dopamine receptors in MPTP parkinsonian monkeys following L-dopa treatment.

Abstract

Twenty-two monkeys (Macaca fascicularis) were utilized in this study. Ten animals were rendered parkinsonian with serial injections of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). Five of these parkinsonian monkeys received L-dopa/carbidopa treatment, and five animals did not. The remaining twelve animals did not receive MPTP. Eight of these animals… (More)

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@article{Alexander1993ChangesIB, title={Changes in brain dopamine receptors in MPTP parkinsonian monkeys following L-dopa treatment.}, author={Guillermo M. Alexander and Robert Jay Schwartzman and John R. Grothusen and Laura Brainard and Sarah W Gordon}, journal={Brain research}, year={1993}, volume={625 2}, pages={276-82} }