Changes in brain catecholamine levels following DL-dopa are not potentiated by deuterium substitution.

Abstract

Adult male Wistar rats were treated with either DL-dopa, D3-DL-dopa or vehicle and sacrificed at various time intervals after treatment. Brain dopamine and noradrenaline concentrations were measured using quantitative mass spectrometric analysis. After treatment with DL-dopa or D3-DL-dopa, total dopamine levels increased above control values; however, no… (More)

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@article{Dewar1985ChangesIB, title={Changes in brain catecholamine levels following DL-dopa are not potentiated by deuterium substitution.}, author={Ken Dewar and Lana Dyck and David A. Durden and Aaron Boulton}, journal={Progress in neuro-psychopharmacology & biological psychiatry}, year={1985}, volume={9 5-6}, pages={675-80} }