Changes in arterial blood pressure after single oral administration of milk-casein-derived peptides in spontaneously hypertensive rats.

@article{Miguel2010ChangesIA,
  title={Changes in arterial blood pressure after single oral administration of milk-casein-derived peptides in spontaneously hypertensive rats.},
  author={Marta Miguel and Jos{\'e} {\'A}ngel G{\'o}mez-Ruiz and Isidra Recio and Amaya Aleixandre},
  journal={Molecular nutrition & food research},
  year={2010},
  volume={54 10},
  pages={1422-7}
}
In this study we evaluated the short-term oral antihypertensive effect of several peptide sequences isolated from casein fractions, previously characterized as in vitro angiotensin-converting enzyme-inhibitors, in spontaneously hypertensive rats (SHR). Systolic blood pressure (SBP) and the diastolic blood pressure (DBP) of the rats were measured by the tail cuff method before administration and also 2, 4, 6, 8 and 24 h post-administration. The sequences LVYPFTGPIPN, HLPLP, IAK, YAKPVA and… CONTINUE READING

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