Changes in adipose-derived inflammatory cytokines and chemokines after successful lifestyle intervention in obese children.

@article{Roth2011ChangesIA,
  title={Changes in adipose-derived inflammatory cytokines and chemokines after successful lifestyle intervention in obese children.},
  author={Christian L Roth and Mario Kratz and Melissa M Ralston and Thomas Reinehr},
  journal={Metabolism: clinical and experimental},
  year={2011},
  volume={60 4},
  pages={445-52}
}
Obesity has been associated with low-grade chronic systemic inflammation, potentially leading to insulin resistance. This study was designed to examine relationships between cardiovascular risk factors, insulin resistance, and simultaneously measured inflammatory parameters in obese children. We examined serum inflammatory parameters in 115 obese children and 30 normal-weight controls; 62 obese children were followed longitudinally in a 1-year obesity intervention study. Serum concentrations of… CONTINUE READING