Changes in adenosine deaminase activity in ageing cultured human cells and the role of zinc.

@article{Ghneim2003ChangesIA,
  title={Changes in adenosine deaminase activity in ageing cultured human cells and the role of zinc.},
  author={Hazem K Ghneim and Saad S. M. Al-Saleh and Fahad J. Al-Shammary and Z S Kordee},
  journal={Cell biochemistry and function},
  year={2003},
  volume={21 3},
  pages={
          275-82
        }
}
The level of adenosine deaminase (ADA; EC 3.5.4.4) was estimated at different passages in six confluent fibroblast cultures established from forearm skin biopsies of healthy adult normal volunteers. After determination of the zinc concentration in standard growth medium, ADA activity was estimated at different passages of subculture in media with different zinc concentrations. The results indicated that the specific activity of ADA in control confluent skin fibroblast cultures (passage 2… CONTINUE READING

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