Changes in a surface-labelled galactoprotein and in glycolipid concentrations in cells transformed by a temperature-sensitive polyoma virus mutant

@article{Gahmberg1974ChangesIA,
  title={Changes in a surface-labelled galactoprotein and in glycolipid concentrations in cells transformed by a temperature-sensitive polyoma virus mutant},
  author={Carl G Gahmberg and D Kiehn and Sen-itiroh Hakomori},
  journal={Nature},
  year={1974},
  volume={248},
  pages={413-415}
}
IN hamster cells transformed by a temperature-sensitive mutant of polyoma virus we have found that the external label in a galactoprotein disappears and the cellular concentration of lactosylceramide increases when the cells are grown at the permissive temperature. These changes can be reversed at the non-permissive temperature. 

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