Changes in Rab3D expression and distribution in the acini of Sjögren's syndrome patients are associated with loss of cell polarity and secretory dysfunction.

@article{Bahamondes2011ChangesIR,
  title={Changes in Rab3D expression and distribution in the acini of Sj{\"o}gren's syndrome patients are associated with loss of cell polarity and secretory dysfunction.},
  author={V. Valentina Bahamondes and Amelina Albornoz and Sergio Aguilera and Cecilia Alliende and Claudio Molina and Isabel Castro and Ulises Urzua and Andrew Frederick Geoffery Quest and Mar{\'i}a-Jos{\'e} Barrera and Sergio Gonzalez and Marianela S{\'a}nchez and Steffen H{\"a}rtel and Marcela Alejandra Hermoso and Cecilia Leyton and M. Feldstedt Gonz{\'a}lez},
  journal={Arthritis and rheumatism},
  year={2011},
  volume={63 10},
  pages={
          3126-35
        }
}
OBJECTIVE Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, requires the participation of Rab family GTPases. This study was undertaken to analyze the expression and localization of Rab3D and Rab8A and to examine their correlation with acinar cell polarity and glandular secretory function. METHODS Nineteen patients with SS and 17… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 17 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 39 REFERENCES

Similar Papers

Loading similar papers…