Changes in Quality of Life in Parkinson's Disease: How Large Must They Be to Be Relevant?

Abstract

BACKGROUND Minimal clinically important difference (MCID) is the smallest change in an outcome, which a patient identifies as meaningful. Although the 2 most frequently applied Parkinson's disease (PD) "quality of life" questionnaires (the PDQ-39 and PDQ-8) provide encouragingly similar results, their MCID thresholds appear to be vastly different. Our aim… (More)
DOI: 10.1159/000455863

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