Changes in Prefrontal-Limbic Function in Major Depression after 15 Months of Long-Term Psychotherapy

@inproceedings{Buchheim2012ChangesIP,
  title={Changes in Prefrontal-Limbic Function in Major Depression after 15 Months of Long-Term Psychotherapy},
  author={A. F. G{\"u}nther Buchheim and Roberto Viviani and Henrik Kessler and Horst K{\"a}chele and Manfred Cierpka and Gerhard D. Roth and Carol Neufeld George and Otto Kernberg and Georg Bruns and Svenja Taubner},
  booktitle={PloS one},
  year={2012}
}
Neuroimaging studies of depression have demonstrated treatment-specific changes involving the limbic system and regulatory regions in the prefrontal cortex. While these studies have examined the effect of short-term, interpersonal or cognitive-behavioural psychotherapy, the effect of long-term, psychodynamic intervention has never been assessed. Here, we investigated recurrently depressed (DSM-IV) unmedicated outpatients (N = 16) and control participants matched for sex, age, and education (N… CONTINUE READING

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