Changes in Platelet P-Selectin and in Plasma C-Reactive Protein in Acute Atherosclerotic Ischemic Stroke Treated with a Loading Dose of Clopidogrel

Abstract

Background: The surface expression of P-selectin on platelets contributes to the progression of inflammatory processes and thrombosis in atherothrombosis. In this study, we showed that the combination regimen of clopidogrel with aspirin could downregulate the P-selectin expression on platelets and the plasma concentration of C-reactive protein (CRP) in… (More)
DOI: 10.1023/A:1023237029550

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