Changes in Plasma Mass-Spectral Profile in Course of Treatment of Non-small Cell Lung Cancer Patients with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

@article{Lazzari2012ChangesIP,
  title={Changes in Plasma Mass-Spectral Profile in Course of Treatment of Non-small Cell Lung Cancer Patients with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors},
  author={Chiara Lazzari and Anna Spreafico and Angela Bachi and Heinrich Roder and Irene C Floriani and Daniela Garavaglia and Angela Cattaneo and Julia Grigorieva and Maria Grazia Vigan{\'o} and Cristina Sorlini and Domenico Ghio and Maxim Tsypin and Alessandra Bulotta and Luca Bergamaschi and Vanesa Gregorc},
  journal={Journal of Thoracic Oncology},
  year={2012},
  volume={7},
  pages={40-48}
}
Introduction: Our previous study showed that pretreatment serum or plasma Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry may predict clinical outcome of non-small cell lung cancer (NSCLC) patients treated with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). In this study, plasma proteomic profiles of NSCLC patients were evaluated in the course of EGFR TKIs therapy. Materials and Methods: Plasma samples were collected at baseline, in the… 
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