Changes in Plasma Mass-Spectral Profile in Course of Treatment of Non-small Cell Lung Cancer Patients with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

@article{Lazzari2012ChangesIP,
  title={Changes in Plasma Mass-Spectral Profile in Course of Treatment of Non-small Cell Lung Cancer Patients with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors},
  author={C. Lazzari and A. Spreafico and A. Bachi and H. Roder and I. Floriani and D. Garavaglia and A. Cattaneo and J. Grigorieva and M. G. Vigan{\'o} and C. Sorlini and D. Ghio and M. Tsypin and A. Bulotta and L. Bergamaschi and V. Gregorc},
  journal={Journal of Thoracic Oncology},
  year={2012},
  volume={7},
  pages={40-48}
}
  • C. Lazzari, A. Spreafico, +12 authors V. Gregorc
  • Published 2012
  • Medicine
  • Journal of Thoracic Oncology
  • Introduction: Our previous study showed that pretreatment serum or plasma Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry may predict clinical outcome of non-small cell lung cancer (NSCLC) patients treated with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). In this study, plasma proteomic profiles of NSCLC patients were evaluated in the course of EGFR TKIs therapy. Materials and Methods: Plasma samples were collected at baseline, in the… CONTINUE READING
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