Changes in Leydig cell gene expression during development in the mouse.

  title={Changes in Leydig cell gene expression during development in the mouse.},
  author={Peter O'Shaughnessy and Louise Willerton and P J Baker},
  journal={Biology of reproduction},
  volume={66 4},
Developmental changes in the expression of 18 Leydig cell-specific mRNA species were measured by real-time polymerase chain reaction to partially characterize the developmental phenotype of the cells in the mouse and to identify markers of adult Leydig cell differentiation. Testicular interstitial webs were isolated from mice between birth and adulthood. Five developmental patterns of gene expression were observed. Group 1 contained mRNA species encoding P450 side chain cleavage (P450(scc… CONTINUE READING
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