Changes in HOXB6 homeodomain protein structure and localization during human epidermal development and differentiation.

@article{Kmves2000ChangesIH,
  title={Changes in HOXB6 homeodomain protein structure and localization during human epidermal development and differentiation.},
  author={L{\'a}szl{\'o} G. K{\"o}m{\"u}ves and Weifang Shen and Angela Kwong and Eric J. Stelnicki and Sophia Rozenfeld and Yuko Oda and A Blink and Keerthi Krishnan and Billy Lau and Theodora M. Mauro and Corey Largman},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2000},
  volume={218 4},
  pages={636-47}
}
HOX homeodomain proteins are master developmental regulators, which are now thought to function as transcription factors by forming cooperative DNA binding complexes with PBX or other protein partners. Although PBX proteins exhibit regulated subcellular localization and function in the nucleus in other tissues, little data exists on HOX and PBX protein localization during skin development. We now show that the HOXB6 protein is expressed in the suprabasal layer of the early developing epidermis… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…