Changes in European Label and Guideline Adherence After Updated Recommendations for Stroke Thrombolysis: Results From the Safe Implementation of Treatments in Stroke Registry.

@article{Anani2015ChangesIE,
  title={Changes in European Label and Guideline Adherence After Updated Recommendations for Stroke Thrombolysis: Results From the Safe Implementation of Treatments in Stroke Registry.},
  author={Nadim Anani and Michael V. Mazya and Olivier Bill and Rong Chen and Sabine Koch and Mustofa Nurhussien Ahmed and Nils Wahlgren and Tiago Prazeres Moreira},
  journal={Circulation. Cardiovascular quality and outcomes},
  year={2015},
  volume={8 6 Suppl 3},
  pages={
          S155-62
        }
}
BACKGROUND Intravenous thrombolysis (IVT) for acute ischemic stroke is subject to label and guideline contraindications. Updated European guidelines in 2008/2009 recommended IVT in selected patients aged >80 years and stroke onset-to-treatment time 3 to 4.5 hours, which the label still prohibited. Our aim was to compare contraindication nonadherence before and after the guideline update. METHODS AND RESULTS Data on IVT-treated patients with stroke at 232 European hospitals participating in… CONTINUE READING
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