Changes in Cartilage Biomarker Levels During a Transcontinental Multistage Footrace Over 4486 km

@article{Mndermann2017ChangesIC,
  title={Changes in Cartilage Biomarker Levels During a Transcontinental Multistage Footrace Over 4486 km},
  author={Annegret M{\"u}ndermann and Christopher Klenk and Christian Billich and Corina N{\"u}esch and Geert I. Pagenstert and Arno Schmidt-Trucks{\"a}ss and Uwe Sch{\"u}tz},
  journal={The American Journal of Sports Medicine},
  year={2017},
  volume={45},
  pages={2630–2636}
}
Background: Cartilage turnover and load-induced tissue changes are frequently assessed by quantifying concentrations of cartilage biomarkers in serum. To date, information on the effects of ultramarathon running on articular cartilage is scarce. Hypothesis: Serum concentrations of cartilage oligomeric matrix protein (COMP), matrix metalloproteinase (MMP)–1, MMP-3, MMP-9, COL2-3/4C long mono (C2C), procollagen type II C-terminal propeptide (CPII), and C2C:CPII will increase throughout a… CONTINUE READING
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Physiology and Pathophysiology in Ultra-Marathon Running

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