Changes in CB(1) and CB(2) receptors in the post-mortem cerebellum of humans affected by spinocerebellar ataxias.

@article{RodrguezCueto2014ChangesIC,
  title={Changes in CB(1) and CB(2) receptors in the post-mortem cerebellum of humans affected by spinocerebellar ataxias.},
  author={Carmen Rodr{\'i}guez-Cueto and Cristina Benito and Javier Fern{\'a}ndez-Ruiz and Juli{\'a}n Esparza Romero and Mariluz Hern{\'a}ndez-G{\'a}lvez and Mar{\'i}a Natividad G{\'o}mez-Ru{\'i}z},
  journal={British journal of pharmacology},
  year={2014},
  volume={171 6},
  pages={1472-89}
}
BACKGROUND AND PURPOSE Spinocerebellar ataxias (SCAs) are a family of chronic progressive neurodegenerative diseases, clinically and genetically heterogeneous, characterized by loss of balance and motor coordination due to degeneration of the cerebellum and its afferent and efferent connections. Unlike other motor disorders, the possible role of changes in the endocannabinoid system in the pathogenesis of SCAs has not been investigated. EXPERIMENTAL APPROACH The status of cannabinoid receptor… CONTINUE READING