Change of connexin 37 in allergen-induced airway inflammation

  title={Change of connexin 37 in allergen-induced airway inflammation},
  author={Seoung Ju Park and Kyung Sun Lee and So Ri Kim and Kyung Hoon Min and Ka Young Lee and Yeong Hun Choe and Seung Yong Park and Sang Hyun Hong and Yong Chul Lee},
  journal={Experimental & Molecular Medicine},
Gap junction channels formed with connexins directly link to the cytoplasm of adjacent cells and have been implicated in intercellular signaling. Connexin 37 (Cx37) is expressed in the gas-exchange region of the lung. Recently, Cx37 has been reported to be involved in the pathogenesis of inflammatory disease. However, no data are available on the role of Cx37 in allergic airway inflammatory disease. In the present study, we used a murine model of ovalbumin (OVA)-induced allergic airway disease… CONTINUE READING


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