Change of ascending reticular activating system with recovery from vegetative state to minimally conscious state in a stroke patient

  title={Change of ascending reticular activating system with recovery from vegetative state to minimally conscious state in a stroke patient},
  author={Sung Ho Jang and Chul Hoon Chang and Young Jin Jung and You Sung Seo},
Rationale: We report on a stroke patient who showed change of the ascending reticular activating system (ARAS) concurrent with recovery from a vegetative state (VS) to a minimally conscious state (MCS), which was demonstrated on diffusion tensor tractography (DTT). Patient concerns: A 59-year-old male patient underwent CT-guided stereotactic drainage 3 times for management of intracerebral hemorrhage and intraventricular hemorrhage. Diagnosis: After 4 months from onset, when starting… Expand
9 Citations
Effect of repetitive transcranial magnetic stimulation on the ascending reticular activating system in a patient with disorder of consciousness: a case report
Increases in neural TV in the right prefrontal lobe of the upper ARAS that were associated with the periods of rTMS application were demonstrated in a stroke patient with DOC. Expand
Recovery of the ascending reticular activating system and consciousness following comprehensive management in a patient with traumatic brain injury.
  • Sung Ho Jang, Young Hyeon Kwon
  • Medicine
  • Yeungnam University journal of medicine
  • 2021
We report on changes in the ascending reticular activating system (ARAS) concurrent with the recovery of impaired consciousness following rehabilitation and cranioplasty in a patient with traumaticExpand
Recovery of consciousness after a brainstem cavernous malformation hemorrhage: A descriptive study of preserved reticular activating system with tractography
These affected fibers of the ARAS, as well as the FA value abnormalities in 2 patients, with recovery of a transient disorder of consciousness after a BSCM hemorrhage are described. Expand
Recovery of an injured ascending reticular activating system with recovery from a minimally conscious state to normal consciousness in a stroke patient: a diffusion tensor tractography study
DTT findings of an injured ARAS during recovery from a minimally conscious state (MCS) to normal consciousness in a stroke patient are reported on. Expand
Single unit activities recorded in the thalamus and the overlying parietal cortex of subjects affected by disorders of consciousness
The findings, albeit obtained in a limited number of patients, unveil the neurophysiology of these conditions at single unit resolution and might be relevant for inspiring novel therapeutic options. Expand
Demystifying White Matter Injury in the Unconscious Patients with Diffusion Tensor Imaging
DTI can be useful as a critical tool for revealing the anatomical basis for the cognitive dysfunction and unconsciousness and can be possibly used to prognosticate patient recovery. Expand
Tractography in Neurosurgery: A Systematic Review of Current Applications.
The ability to visualize the brain's fiber connections noninvasively in vivo may potentially be able to predict clinical deficits and rehabilitation potential, as well as finding possible explanations for neurologic disorders in retrospect, in this systematic review of current applications. Expand
Variation of Cognitive Function During a Short Stay at Hypobaric Hypoxia Chamber (Altitude: 3842 M)
Cerebral Blood Flow index does not seem to be the physiological measurement of choice to hypoxia explaining the maintenance of cognitive performance after acute exposure to hypobaric Hypoxia and requires further investigation. Expand
COVID-19 related leukoencephalopathy with bilateral reticular formation involvement
The imaging findings of COVID-19-related leukoencephalopathy associated with bilateral reticular formation diffusion restriction in brain magnetic resonance imaging are presented. Expand


Recovery From Vegetative State to Minimally Conscious State: A Case Report.
A patient with brain injury who showed change of the ARAS concurrent with the recovery from a VS and a MCS is reported on. Expand
Ascending reticular activating system recovery in a patient with brain injury
Diffusion tensor tractography (DTT), derived from diffusion tensor imaging (DTI), enables 3D reconstruction and approximation of the ARAS in the human brain and reports on a patient with HI-BI with ARAS recovery. Expand
Recovery of injured lower portion of the ascending reticular activating system in a patient with traumatic brain injury.
Recovered lower portion of the ascending reticular activating system (ARAS) between the pontine reticular formation and the thalamus in a patient with traumatic brain injury is demonstrated. Expand
Assessment of functional connectivity between the ascending reticular activating system (ARAS) and a polymodal associative cortex and neuroimaging allows the assessment of anatomic and functional disturbances in severely braininjured patients, providing new understanding into the pathophysiology of consciousness generation. Expand
Diffusion weighted imaging distinguishes the vegetative state from the minimally conscious state
The vegetative (VS) and minimally conscious (MCS) states are currently distinguished on the basis of exhibited behaviour rather than underlying pathology. Although previous histopathological studiesExpand
Brain function in coma, vegetative state, and related disorders
We review the nosological criteria and functional neuroanatomical basis for brain death, coma, vegetative state, minimally conscious state, and the locked-in state. Functional neuroimaging isExpand
Wakefulness and loss of awareness
During persistent vegetative state, a hypermetabolism in the ascending reticular activating system (ARAS) and impaired functional connectivity between the ARAS and the precuneus is identified, which strengthens the hypothesis that consciousness is based on a widespread neural network. Expand
The ascending reticular activating system from pontine reticular formation to the hypothalamus in the human brain: A diffusion tensor imaging study
The reconstruction methodology and the results of this study would be useful to clinicians involved in the care of patients with impaired consciousness and researchers in studies of the ARAS. Expand
Recovery of consciousness after brain injury: a mesocircuit hypothesis
  • N. Schiff
  • Psychology, Medicine
  • Trends in Neurosciences
  • 2010
A "mesocircuit" model is proposed that predicts specific roles for different structural and dynamic changes that may occur gradually during recovery of consciousness following severe brain injuries. Expand
The Ascending Reticular Activating System from Pontine Reticular Formation to the Thalamus in the Human Brain
The reconstructed ARAS originated from the pontine RF, ascended through the mesencephalic tegmentum just posterior to the red nucleus, and then terminated on the intralaminar nuclei of the thalamus. Expand