Change in surface roughness by dynamic shape-memory acrylate networks enhances osteoblast differentiation.

@article{Lee2016ChangeIS,
  title={Change in surface roughness by dynamic shape-memory acrylate networks enhances osteoblast differentiation.},
  author={Erin M. Lee and Kathryn E Smith and Ken Gall and Barbara D Boyan and Zvi Schwartz},
  journal={Biomaterials},
  year={2016},
  volume={110},
  pages={34-44}
}
Microscale surface roughness has been shown to enhance osseointegration of titanium implants through increased osteoblast differentiation while osteoblast proliferation remains greater on smooth titanium. Taking advantage of these phenomena, we developed a shape memory (meth)acrylate copolymer with thermomechanical properties that created a time-dependent dynamic surface change from smooth to rough under in vitro cell culture conditions and evaluated the effect of the shape recovery on… CONTINUE READING
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